Some of the larger animals found in the Appalachian region are moose, black bears, elk. Some of the smaller animals found in the Appalachian region are squirrels, chipmunks, salamanders, raccoons, and opossums. As well as some rarer species such as fox, porcupine, mink and muskrats. Many different types of snakes, both poisonous and non poisonous are found in the woods and rocky areas. In the streams and ponds have many trout, catfish, bass, and bream are found.
The trees in the Appalachian region are described as a mixture of deciduous with oaks and hickories. There are spruce and firs to the north. To the south end of the mountains it is the most diverse than any other forest in North America including basswood, tulip trees, ash and magnolia to the mix. In 1999 the number of plants recorded was 6374, but scientist think that the number would be more accurate if it were 5 or 6 times that number.